When Lord Buddha spoke about suffering, he wasn't referring simply to superficial problems like illness and injury, but to the fact that the dissatisfied nature of the mind itself is suffering. No matter how much of something you get, it never satisfies your desire for better or more. This unceasing desire is suffering; its nature is emotional frustration.
Suffering is the basic lot of mankind. The only way to end suffering is by purifying the mind. The individual creates his own suffering and it is he alone who can end it.
It is not the eye, nor the ear, which hold us bound to the wheel of suffering, nor is it the things perceived by the eye, or the ear. It is the desire of the one for the other that is the fetter. If the eye and the ear are not attached to things seen and heard, then there is no sorrow or suffering.
Suffering arises from desiring, wanting and craving. One escape from the burden of suffering when one is liberated from your self and its desires.
Suffering follows the evil act as the wheel of the cart follows the foot of the ox that draws it.